Adhumulone

Bio-Activity Analysis
Adhumulone Potency by Source
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Metabolic Support: Early research suggests it helps the body process sugars and fats more efficiently.
- Anti-Inflammatory Properties: It acts on specific inflammatory pathways, potentially reducing chronic low-grade inflammation.
- Cellular Defense: It may help protect cells from oxidative stress.
Deep Dive
Adhumulone belongs to a family of compounds called prenylated phloroglucinol derivatives. In simple terms, it is a bioactive compound found in the lupulin glands of the hop plant.
Scientists are interested in how Adhumulone interacts with the body's metabolism. One of the key mechanisms involves activating an enzyme called AMPK (often called the 'metabolic master switch'). When AMPK is active, it signals your cells to burn more energy and improve insulin sensitivity. This is why Adhumulone is often marketed as a support for healthy blood sugar levels and weight management, distinct from the sedative effects of other hop compounds.
Natural Food Sources
It is important to note that Adhumulone is found almost exclusively in Hops (Humulus lupulus). While hops are used in beer, the concentration in a supplement is much higher and does not involve alcohol.
| Food | Amount | % DV |
|---|---|---|
| Hops Extract | High | N/A |
| Beer | Trace | N/A |
| Hops Tea | Moderate | N/A |
Supplementation
Dosage: Clinical studies typically use extracts standardized to contain between 1% to 5% Adhumulone. Dosages often range from 300mg to 600mg daily, depending on the extract potency.
Who should take it: Individuals looking for metabolic support or those seeking natural alternatives for managing blood sugar levels (always under doctor supervision).
Food First: Because this is a specialized compound, you cannot get a therapeutic dose from food alone; it requires a concentrated hop extract supplement.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety Profile
Side Effects: Generally well-tolerated. Mild gastrointestinal upset (nausea, stomach cramping) can occur.
Interactions: Because it may affect blood sugar and blood pressure, it should be used with caution by those taking medication for diabetes or hypertension.
Who Should Avoid: Pregnant or breastfeeding women should avoid high-dose hop supplements due to a lack of safety data. Individuals with hormone-sensitive conditions (such as breast cancer or endometriosis) should consult a doctor, as hops can have weak estrogenic effects, though Adhumulone is less associated with this than other hop compounds.
Scientific References
- [1]Yajima, H., et al. (2014). 'Effect of Adhumulone on Obesity and Glucose Intolerance.' *Journal of Natural Medicines*.
- [2]Yasukawa, K., et al. (2010). 'Anti-inflammatory activity of hop derived compounds.' *Phytotherapy Research*.
- [3]National Institutes of Health (NIH) - Office of Dietary Supplements: Hops (*Humulus lupulus*) Fact Sheet.