Adrafinil

Bio-Activity Analysis
Onset Time: Adrafinil vs Modafinil
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why People Take It
- Combats Excessive Sleepiness: Primarily used to promote wakefulness in those with sleep disorders.
- Enhances Focus: Users often report a significant increase in mental clarity and concentration.
- Mood Elevation: It may provide a subtle boost in motivation and overall well-being.
How It Works
Adrafinil works by stimulating the production of Histamine and Orexin in the brain, which are chemical messengers responsible for keeping you awake and alert. It also influences the Hypothalamus, the area of the brain that regulates sleep cycles. By boosting these neurotransmitters, it effectively signals your body to remain in a state of high alertness, delaying the urge to sleep and reducing mental fatigue.
Natural Alternatives (Food Sources)
Since Adrafinil is a synthetic drug, there are no natural food sources. However, you can support your energy levels naturally through your diet. Here are the best foods for natural alertness:
| Food | Amount | % DV (Daily Value) |
|---|---|---|
| Matcha Green Tea | 1 Cup | High (L-Theanine) |
| Dark Chocolate (85%) | 1 oz | Moderate (Theobromine) |
| Walnuts | 1/4 Cup | High (Omega-3s) |
| Spinach | 1 Cup | High (Iron/Magnesium) |
| Eggs | 2 Large | High (Choline) |
Supplementation
Adrafinil is typically taken in tablet form. It is not a regulated medication in many countries (including the USA, where it is unapproved by the FDA but not strictly banned). It is often used 'on demand' rather than daily, as tolerance can build up. Note that because it metabolizes through the liver, it requires time to take effect (usually 45-60 minutes).
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety & Warnings
Who Should Avoid It:
- Individuals with liver or kidney issues (it puts stress on the liver).
- Those with heart conditions or high blood pressure.
- Pregnant or breastfeeding women.
Side Effects & Interactions:
- Liver Toxicity: Long-term use can elevate liver enzymes. Periodic liver function tests are recommended.
- Side Effects: Insomnia, headaches, agitation, stomach upset, and high blood pressure.
- Interactions: It may interact with anti-depressants (SSRIs), anti-anxiety medications, and other stimulants.
Disclaimer: This is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting this supplement.
Scientific References
- [1]Duteil, J., et al. (1979). 'Adrafinil, a new psychostimulant.' *European Journal of Pharmacology*.
- [2]Bastuji, H., & Jouvet, M. (1988). 'Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil.' *Progress in Neuro-Psychopharmacology and Biological Psychiatry*.
- [3]FDA Warning Letters regarding Adrafinil sales (regarding unapproved drug status).