Health Guide
Andarine
Andarine (S-4) is a synthetic Selective Androgen Receptor Modulator (SARM) developed for medical conditions like muscle wasting and osteoporosis. Unlike common nutrients, it is not found in nature and is not approved for human consumption. While it promises muscle growth and fat loss, it carries severe risks, most notably vision toxicity (yellow tint/night blindness) and suppression of natural testosterone.
Evidence BasedDietary Supplement
VERIFIED SOURCE
Bio-Activity Analysis
Reported Side Effect Incidence (Andarine)
SCIENTIFIC DATA VISUALIZATION
Y-Axis
Reported Frequency
Side Effect →
Health Benefits & Sources
Why It Is Researched
- Muscle Growth: Mimics testosterone to stimulate lean mass.
- Bone Density: Increases bone mineral density.
- Fat Loss: Promotes lipolysis (breaking down fat).
The Reality
While the animal studies showed promise for treating atrophy, the side effects in humans—specifically regarding vision—have halted widespread clinical development. Natural protein intake and resistance training remain the safest methods for these goals.
Natural Food Sources
Andarine is a synthetic chemical and is not found in food. To support similar goals (muscle/bone health) naturally, consume:
| Food | Nutrient | Goal |
|---|---|---|
| Salmon | Vit D / Protein | Bone Health / Muscle |
| Eggs | Protein / Choline | Muscle Synthesis |
| Spinach | Magnesium | Muscle Function |
Supplementation
Do not supplement Andarine. It is often sold illegally or as a 'research chemical.' For legal muscle support, consider Creatine Monohydrate or Whey Protein.
Top Food Sources
Salmon
Natural Vit D & Omega-3s for bone health
Lean Beef
Natural Creatine & Protein for muscle
Eggs
Complete amino acid profile
Spinach
Magnesium for muscle function
Greek Yogurt
Calcium for bone density
Frequently Asked Questions
It is not FDA-approved for human use. It is legal to possess as a 'research chemical' in many places, but banned by WADA for athletes.
Many users report that the yellow tint and night blindness persist even after stopping the compound, suggesting potential permanent retinal changes.
Yes. Andarine suppresses natural testosterone production, so a Post Cycle Therapy (PCT) protocol is usually required to restore hormonal balance.
Yes. Creatine Monohydrate, Beta-Alanine, and high-protein diets are legal, safe, and effective for performance enhancement.
Safety & Side Effects
CRITICAL SAFETY WARNING
- Vision Damage: Users report a permanent yellow tint to vision and difficulty seeing in low light. This is considered a toxicity signal from the retina.
- Hormone Crash: It suppresses natural testosterone, requiring Post Cycle Therapy (PCT) to recover.
- Liver Stress: Potential hepatotoxicity.
- Legal Status: Banned by the World Anti-Doping Agency (WADA) and most sports federations.
Scientific References
- [1]US Patent 7,932,229 (GTX, Inc.) - Original development patent for enobosarm (S-4).
- [2]Clinical Trial NCT00655461 - Study on SARMs for functional ability in older women.
- [3]Journal of Pharmacology and Experimental Therapeutics - Studies on tissue selectivity.