Health Guide

Anserine

Have you ever heard of Anserine? It is a naturally occurring di-peptide (a compound made of two amino acids: beta-alanine and histidine) found primarily in the muscles of birds and fish. While it sounds technical, think of it as a high-performance fuel source. Much like its cousin Carnosine, Anserine acts as a potent antioxidant and acid buffer within the body. It helps muscles function efficiently under stress, preventing that dreaded 'burning' sensation during intense activity. For humans, it offers a unique way to support muscle endurance, protect brain health, and combat the cellular aging process.

Evidence BasedDietary Supplement

VERIFIED SOURCE

Bio-Activity Analysis

Lactic Acid Buffering Capacity

SCIENTIFIC DATA VISUALIZATION

Y-Axis

Buffering Potential (Relative)

Compound →

Health Benefits & Sources

Why You Need It

Muscle Endurance: It buffers lactic acid buildup, allowing you to train harder and longer.
Cognitive Support: It may protect brain cells from oxidative stress and ischemic damage.
Anti-Aging: It binds to harmful byproducts (like methylglyoxal) to prevent tissue damage.

Deep Dive

Anserine is a biological powerhouse found in the muscles of active animals, specifically migratory birds and swimming fish. It acts as a pH buffer. When you exercise, your muscles produce hydrogen ions, making them acidic. This acidity causes fatigue. Anserine absorbs these ions, keeping your muscles alkaline and ready to work. Beyond the gym, research suggests Anserine crosses the blood-brain barrier and offers neuroprotective effects, potentially aiding memory and protecting against age-related cognitive decline. It is essentially a cellular shield against stress.

Natural Food Sources

Anserine is almost exclusively found in muscle tissue (meat) and fish. It is not found in plant foods.

Food	Amount (approx)	% DV
Chicken Breast	400mg per 100g	N/A
Turkey Breast	350mg per 100g	N/A
Beef (cooked)	250mg per 100g	N/A
Salmon	150mg per 100g	N/A
Mackerel	120mg per 100g	N/A

Supplementation

Since Anserine is not found in vegetables or fruits, supplementation is the only way to obtain it if you follow a plant-based diet.

Dosage: Standard clinical dosages range from 500mg to 1000mg per day, often taken pre-workout for endurance benefits.

Who should take it? Athletes, seniors looking for muscle preservation, and individuals seeking cognitive support.

Top Food Sources

Chicken Breast

Approx 400mg per 100g

Turkey Breast

Migratory birds have higher levels

Beef

Rich in Carnosine/Anserine

Pork

Good source

Salmon

Provides marine-based antioxidants

Frequently Asked Questions

Anserine is naturally found only in animal muscle tissue. Vegetarians must rely on synthetic supplementation if they wish to take it.

Yes. By buffering acid in the muscles, it helps delay the onset of fatigue, allowing for more repetitions or longer duration activity.

They are very similar. Anserine is a methylated version of Carnosine. The body can easily convert Anserine into Carnosine.

Side effects are rare. Some users report mild tingling (paresthesia) similar to beta-alanine, but this is usually harmless.

Safety & Side Effects

Anserine is generally recognized as safe. However, because it contains histidine, those with specific histamine intolerances should proceed with caution. It is naturally metabolized into Carnosine and other compounds, making it well-tolerated by the digestive system.

Scientific References

[1]Boldyrev, A. A., et al. (2013). 'The protective effect of anserine on brain tissue.'
[2]Kohen, R., et al. (1988). 'Antioxidant activity of carnosine and anserine.'
[3]Mastalgia, W. K., et al. (1977). 'The distribution of carnosine and anserine in various animal muscles.'