Boswellic Acid

Bio-Activity Analysis
Mechanism of Action: 5-LOX Inhibition
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Joint Comfort & Mobility: Significantly reduces pain and stiffness in osteoarthritis and rheumatoid arthritis.
- Gut Health Support: Helps manage inflammatory bowel diseases like Crohn's and ulcerative colitis by reducing intestinal inflammation.
- Respiratory Function: Acts as a bronchodilator, helping to open airways and ease breathing in conditions like asthma.
- Cognitive Health: May support brain health by reducing neuroinflammation.
Deep Dive
Boswellic Acid works by inhibiting an enzyme called 5-lipoxygenase (5-LOX). This enzyme produces leukotrienes, which are inflammatory molecules that contribute to swelling, pain, and bronchoconstriction. By blocking this pathway, Boswellic Acid effectively 'turns down the volume' on chronic inflammation. Clinical studies have shown that it can be as effective as some NSAIDs for osteoarthritis pain, but it does not cause the stomach irritation or ulceration commonly associated with long-term NSAID use.
Natural Food Sources
Important Note: Boswellic Acid is not found in fruits or vegetables. It is a specific resin extracted from the Boswellia tree. You cannot obtain therapeutic amounts through diet alone; supplementation is required.
| Food Source | Form | Active Compound |
|---|---|---|
| Boswellia serrata Resin | Gum Resin | Boswellic Acids (AKBA is most potent) |
| Incense (Frankincense) | Burned/Inhaled | Trace amounts (not therapeutic for ingestion) |
Supplementation
- Dosage: Therapeutic doses typically range from 300mg to 500mg, taken 2 to 3 times daily. Look for extracts standardized to contain at least 60% Boswellic Acids or specifically 30-40% AKBA (Acetyl-11-keto-beta-boswellic acid).
- Who Should Take It: Individuals suffering from joint pain, osteoarthritis, inflammatory bowel issues, or asthma.
- Timing: Take with meals to enhance absorption and minimize potential stomach upset.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Generally considered safe and well-tolerated. Mild side effects are rare but may include nausea, digestive upset, or skin rash.
Who Should Avoid It:
- Pregnant/Breastfeeding Women: Due to lack of safety data.
- Bleeding Disorders: Boswellic Acid may slow blood clotting; avoid if you have a bleeding condition or are taking blood thinners (Warfarin, Aspirin).
- Surgery: Stop taking at least 2 weeks before scheduled surgery.
- Autoimmune Diseases: Because it stimulates the immune system, it might worsen symptoms of multiple sclerosis, lupus, or rheumatoid arthritis in some cases.
Scientific References
- [1]Ethier, A. S., et al. (2021). 'Boswellia serrata for treating osteoarthritis.' *Expert Review of Clinical Pharmacology*.
- [2]Gupta, I., et al. (2001). 'Effects of Boswellia serrata gum resin in patients with bronchial asthma.' *European Journal of Medical Research*.
- [3]Grunwald, D. (2018). 'Boswellic acids in inflammatory bowel disease.' *Zeitschrift für Phytotherapie*.