DrFeb
Health Guide

C-Phycocyanin

Have you heard of the 'blue gold' from the ocean? C-Phycocyanin is a vibrant blue pigment found exclusively in Spirulina (a blue-green algae). But it's much more than just a natural food coloring! It is a potent antioxidant and anti-inflammatory compound that scientists are studying for its potential to protect your cells. While it is technically a chemical compound, it is 100% natural and safe to consume. Think of it as nature's shield, helping your body fight off stress and wear-and-tear.
Evidence BasedDietary Supplement
C-Phycocyanin
VERIFIED SOURCE

Bio-Activity Analysis

Antioxidant Potency Comparison (ORAC Value)

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Relative Antioxidant Score
Compound →

Health Benefits & Sources

Why You Need It

  • Powerful Antioxidant: It helps neutralize harmful free radicals in your body.
  • Anti-Inflammatory: It may help calm inflammation, which is the root of many chronic diseases.
  • Brain Health: Early studies suggest it might help protect brain cells from damage.
  • Exercise Recovery: It can help reduce muscle damage after a tough workout.

Deep Dive

C-Phycocyanin (often called C-PC) works by stimulating your body's own antioxidant enzymes, like superoxide dismutase (SOD). Unlike synthetic supplements, this pigment is a 'chromoprotein,' meaning it binds to protein, making it easier for your body to utilize.

Its most exciting benefit is its ability to inhibit the production of inflammatory signaling molecules (like prostaglandins and leukotrienes). By keeping inflammation low, you support your heart, brain, and metabolic health naturally.

Natural Food Sources

The primary natural source of C-Phycocyanin is Spirulina. You cannot find it in fruits or vegetables. To get the most benefit, look for high-quality Spirulina supplements that retain the blue pigment (avoid over-processed green tablets).

FoodAmount (per 10g serving)% Daily Value (Est.)
Spirulina Powder600mg - 1000mgHigh
Spirulina Tablets200mg - 500mgMedium
Blue Spirulina Extract500mg - 800mgHigh

Supplementation

Dosage:

  • Dietary Intake: 1g to 5g of Spirulina daily usually provides 100-500mg of Phycocyanin.
  • Standardized Extracts: Studies often use 200mg to 500mg of pure C-Phycocyanin extract per day.

Who should take it?

  • Individuals looking for natural antioxidant support.
  • Athletes seeking faster recovery.
  • Those wanting to support cognitive function as they age.

Always take with a meal to aid absorption.

Top Food Sources

Spirulina Powder
Best natural source, approx 15% by weight
Blue Spirulina (Extract)
Purified form, almost exclusively Phycocyanin
Spirulina Tablets
Convenient, check for fillers
AFA Algae (Klamath)
Contains some, but less than Spirulina
Chlorella
Green algae, does not contain Phycocyanin

Frequently Asked Questions

Not exactly. Spirulina is the whole plant (algae), while C-Phycocyanin is the specific blue protein extracted from it. Taking Spirulina is a great way to get it naturally.
It is a phycobiliprotein, a type of pigment that captures light energy. This bright blue color indicates high purity and potency.
No, not in normal doses. While concentrated extracts can stain surfaces, consuming it will not turn your skin or hair blue.
Technically yes, but it is very expensive and rare. Most supplements are derived from natural Spirulina extraction. Always check the label for 'natural source'.

Safety & Side Effects

Safety Profile

C-Phycocyanin is generally recognized as safe (GRAS) when derived from pure Spirulina.

Potential Side Effects:

  • Digestive Discomfort: High doses of Spirulina can cause bloating or gas in some people initially.
  • Allergic Reactions: If you are allergic to seafood or seaweed, you may react to algae-derived supplements. Stop immediately if you experience swelling or hives.

Who should avoid it?

  • Autoimmune Conditions: Because it stimulates the immune system, those with conditions like lupus or rheumatoid arthritis should consult a doctor.
  • Phenylketonuria (PKU): Spirulina contains phenylalanine; avoid if you have this genetic condition.
  • Pregnancy: There is not enough safety data for pregnant or breastfeeding women; stick to food sources only.

Scientific References

  • [1]Sato, N., et al. (2020). 'C-Phycocyanin attenuates oxidative stress and neuronal damage.' *Journal of Nutritional Biochemistry*.
  • [2]Romay, C., et al. (2003). 'Anti-inflammatory activity of C-phycocyanin.' *International Immunopharmacology*.
  • [3]Jensen, G.S., et al. (2016). 'Antioxidant and anti-inflammatory properties of an algae-derived supplement.' *Journal of Medicinal Food*.