Health Guide
Calcium Bisphosphonate
Calcium Bisphosphonate is a bit of a misnomer in the supplement world. Strictly speaking, Bisphosphonates are a class of **prescription drugs** (like Alendronate/Fosamax) used to treat osteoporosis. However, in the context of dietary supplements, you are likely looking for **Bisglycinate Chelate Calcium** (or simply Calcium Bisglycinate). This is a highly bioavailable form of calcium where the mineral is bound to the amino acid glycine. Unlike harsh calcium forms (like carbonate) that can cause stomach upset, this gentle form is easily absorbed by your gut, helping you build strong bones without the digestive drama.
Evidence BasedDietary Supplement
VERIFIED SOURCE
Bio-Activity Analysis
Calcium Absorption Efficiency (Relative)
SCIENTIFIC DATA VISUALIZATION
Y-Axis
Absorption Rate
Form →
Health Benefits & Sources
Why You Need It
- Superior Absorption: Your body utilizes a higher percentage of this calcium compared to cheaper forms like calcium carbonate.
- Gentle on the Stomach: It does not require strong stomach acid to break down, making it ideal for those with sensitive digestion or taking acid-reducing medication.
- Bone Strength: Essential for maintaining bone density and preventing fractures as you age.
- Muscle Function: Helps muscles contract and relax properly, reducing the risk of cramps.
Deep Dive
Calcium is the most abundant mineral in the body, but it needs a vehicle to get into your bloodstream. Calcium Bisglycinate (often confused with Bisphosphonate in casual conversation) uses a process called 'chelation.' The calcium is wrapped in glycine, which allows it to pass through the intestinal wall efficiently. This mimics the way food-based calcium is processed, making it the closest experience to eating a calcium-rich meal.
Natural Food Sources
Remember, the safest and most effective way to get calcium is through your diet. The body is designed to extract calcium from whole foods naturally.
| Food | Amount | % Daily Value (DV) |
|---|---|---|
| Plain Yogurt | 1 cup | ~30% |
| Collard Greens | 1 cup (cooked) | ~27% |
| Sardines (canned) | 3 oz | ~33% |
| Tofu (firm) | ½ cup | ~25% |
| Almonds | 1 oz | ~8% |
Supplementation
- Who needs it: People with lactose intolerance, vegans who don't eat enough greens, or post-menopausal women requiring higher intake.
- Dosage: Typical doses range from 200mg to 500mg per serving. It is best to take smaller doses (500mg max at a time) with food to maximize absorption.
Top Food Sources
Dairy (Yogurt/Milk)
Approx 300mg per cup
Leafy Greens (Kale/Bok Choy)
Best plant source
Canned Salmon/Sardines
Includes Vitamin D
Tofu (Calcium Set)
Check label for 'Calcium Sulfate'
Fortified Plant Milks
Check for Calcium Carbonate vs. Citrate
Frequently Asked Questions
No. This is a common confusion. Prescription Bisphosphonates (like Fosamax) stop bone breakdown. Calcium Bisglycinate (a supplement) feeds bone building. They are often prescribed together.
The chelation process (binding calcium to glycine) is more expensive than grinding up rocks (Calcium Carbonate). You pay for absorption and comfort.
Yes! Vitamin D is actually required for your body to absorb calcium. Taking them together is highly recommended.
Calcium Bisglycinate is the least likely form to cause gas compared to Calcium Carbonate, which requires stomach acid to dissolve.
Safety & Side Effects
Safety & Interactions
CRITICAL CLARIFICATION: If your doctor prescribed actual 'Bisphosphonates' (like Alendronate, Risedronate, or Ibandronate) for osteoporosis, these are strong medications, not dietary supplements. Do not stop taking them without medical advice.
For Calcium Bisglycinate (Supplement):
- Side Effects: Rare and mild. May include loose stools (if you take too much).
- Interactions: Calcium can interfere with the absorption of antibiotics (tetracyclines and quinolones) and iron supplements. Take these 2–4 hours apart.
- Contraindications: People with a history of kidney stones or high blood calcium levels (hypercalcemia) should consult a doctor before supplementing.
Scientific References
- [1]Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium. (2011). *Dietary Reference Intakes for Calcium and Vitamin D*.
- [2]Rude, R. K. (2009). *Magnesium, Calcium, and Bone Health*. In: Handbook of Nutrition and the Kidney.
- [3]Lukert, B. P., & Raisz, L. G. (1990). *Glucocorticoid-induced osteoporosis: Pathogenesis and management*. Annals of Internal Medicine.
- [4]Heaney, R. P. (2009). *Calcium absorption variability and implications for supplement strategies*. Journal of the American College of Nutrition.