Health Guide

Conjugated Linolenic Acid

Conjugated Linoleic Acid (CLA) is a specific type of fatty acid found primarily in meat and dairy from grass-fed animals. Unlike standard fats, CLA is biologically active and plays a key role in regulating metabolism and body composition. While it is often sold as a weight-loss supplement, it is a natural part of a traditional diet. It is prized for its ability to potentially reduce body fat mass and support the immune system without the use of stimulants.
Evidence BasedDietary Supplement
Conjugated Linolenic Acid
VERIFIED SOURCE

Bio-Activity Analysis

CLA Concentration: Grass-Fed vs. Grain-Fed Beef

SCIENTIFIC DATA VISUALIZATION

Y-Axis
CLA (mg per gram of fat)
Cattle Diet

Health Benefits & Sources

Why You Need It

  • Fat Loss: Helps reduce body fat by increasing the rate at which your body burns fat for fuel.
  • Muscle Preservation: Unlike many weight loss aids, CLA helps protect lean muscle tissue during calorie restriction.
  • Immune Function: Acts as an immune modulator, potentially helping the body fight infection more effectively.
  • Metabolic Health: May improve insulin sensitivity, helping regulate blood sugar levels.

Deep Dive

CLA is structurally similar to linoleic acid (an essential omega-6 fat) but arranged differently. It functions as a metabolic regulator. By inhibiting the enzyme lipoprotein lipase, CLA prevents fatty acids from being easily deposited into fat cells. Instead, these fatty acids are directed toward muscle tissue for energy. This shift in nutrient partitioning is why it is favored by athletes looking to achieve a 'lean' look.

Natural Food Sources

The highest concentrations of CLA are found in ruminant animals (cows, sheep, goats) that graze on grass. The CLA content in grain-fed animals is significantly lower.

Top Natural Sources:

  • Grass-Fed Beef (High)
  • Lamb (High)
  • Full-Fat Dairy (Cheese, Butter) from Grass-Fed Cows (Medium-High)
  • Pasture-Raised Eggs (Low-Medium)

Supplementation

CLA supplements are derived from safflower oil. They are best used by those actively trying to lose body fat. A common dose is 3.0 to 6.0 grams daily, split into two or three doses. It is fat-soluble, so take it with a meal containing fat.

Top Food Sources

Grass-Fed Ground Beef
500mg per 100g
Cheddar Cheese
450mg per 100g
Grass-Fed Butter
350mg per 100g
Lamb Chops
520mg per 100g
Pasture-Raised Eggs
150mg per 100g

Frequently Asked Questions

It may produce minor fat loss without exercise, but it is significantly more effective when combined with physical activity.
Current research suggests it is safe for up to 2 years, but long-term safety data beyond that is limited.
If you eat plenty of grass-fed dairy and red meat, you may get enough. However, therapeutic doses for weight loss usually require supplementation.
No, it is technically an Omega-6 fatty acid, but it has different health properties than standard Omega-6s found in vegetable oils.

Safety & Side Effects

Generally recognized as safe (GRAS) in dosages up to 6 grams daily. However, high doses may cause gastrointestinal distress (nausea, stomach cramps). It may interact with blood-thinning medications (like Warfarin) and diabetes medications. Those with liver conditions should exercise caution.

Scientific References

  • [1]Whigham, L. D., et al. (2007). 'Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans.'
  • [2]Belury, M. A. (2002). 'Dietary conjugated linoleic acid in health: physiological mechanisms of action.'
  • [3]Shen, C. L., et al. (2007). 'Dietary conjugated linoleic acid alters bone mineral density and bone composition in rats.'