Conjugated Linolenic Acid

Bio-Activity Analysis
CLA Concentration: Grass-Fed vs. Grain-Fed Beef
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Fat Loss: Helps reduce body fat by increasing the rate at which your body burns fat for fuel.
- Muscle Preservation: Unlike many weight loss aids, CLA helps protect lean muscle tissue during calorie restriction.
- Immune Function: Acts as an immune modulator, potentially helping the body fight infection more effectively.
- Metabolic Health: May improve insulin sensitivity, helping regulate blood sugar levels.
Deep Dive
CLA is structurally similar to linoleic acid (an essential omega-6 fat) but arranged differently. It functions as a metabolic regulator. By inhibiting the enzyme lipoprotein lipase, CLA prevents fatty acids from being easily deposited into fat cells. Instead, these fatty acids are directed toward muscle tissue for energy. This shift in nutrient partitioning is why it is favored by athletes looking to achieve a 'lean' look.
Natural Food Sources
The highest concentrations of CLA are found in ruminant animals (cows, sheep, goats) that graze on grass. The CLA content in grain-fed animals is significantly lower.
Top Natural Sources:
- Grass-Fed Beef (High)
- Lamb (High)
- Full-Fat Dairy (Cheese, Butter) from Grass-Fed Cows (Medium-High)
- Pasture-Raised Eggs (Low-Medium)
Supplementation
CLA supplements are derived from safflower oil. They are best used by those actively trying to lose body fat. A common dose is 3.0 to 6.0 grams daily, split into two or three doses. It is fat-soluble, so take it with a meal containing fat.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Generally recognized as safe (GRAS) in dosages up to 6 grams daily. However, high doses may cause gastrointestinal distress (nausea, stomach cramps). It may interact with blood-thinning medications (like Warfarin) and diabetes medications. Those with liver conditions should exercise caution.
Scientific References
- [1]Whigham, L. D., et al. (2007). 'Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans.'
- [2]Belury, M. A. (2002). 'Dietary conjugated linoleic acid in health: physiological mechanisms of action.'
- [3]Shen, C. L., et al. (2007). 'Dietary conjugated linoleic acid alters bone mineral density and bone composition in rats.'