Endopeptidase

Why You Need It

• Reduces Inflammation & Swelling: Endopeptidases like bromelain disrupt the chemical messengers that cause swelling, making them excellent for recovery after injury or intense exercise.
• Improves Protein Digestion: If you feel heavy or bloated after a high-protein meal, these enzymes help break down meat and legumes efficiently, absorbing more amino acids.
• Speeds Up Wound Healing: By clearing away damaged tissue and reducing fluid buildup, these enzymes support faster skin and tissue repair.

Deep Dive

Endopeptidases work by cutting protein chains at specific internal points (unlike exopeptidases, which snip the ends). This makes them incredibly efficient at digesting complex proteins like collagen. In the context of dietary supplements, Bromelain (from pineapple) and Papain (from papaya) are the stars. Research suggests they can modulate the immune system, potentially helping with sinusitis and respiratory issues by thinning mucus. Because they survive the stomach acid better than many other enzymes, they can exert systemic effects beyond just the gut.

Natural Food Sources

Endopeptidases are abundant in raw fruits. Cooking destroys them, so raw is best!

Supplementation

Supplements usually offer a standardized potency (GDU - Gelatin Digesting Units) of Bromelain or Papain. They are best taken with meals for digestion or between meals for systemic anti-inflammatory effects.