False Calumba

Bio-Activity Analysis
Impact on Immune Cell Activity (Macrophages)
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Immune System Booster: Stimulates the activity of white blood cells to fight off infections.
- Liver Protection: Acts as a hepatoprotective agent, helping detoxify the liver from toxins and alcohol.
- Stress & Anxiety Relief: Functions as an adaptogen, balancing cortisol levels to improve resilience to stress.
- Anti-Inflammatory: Reduces systemic inflammation, easing joint pain and arthritic symptoms.
Deep Dive
False Calumba contains alkaloids like berberine and tinosporin, which are responsible for its therapeutic effects. Unlike stimulants that give you a temporary energy spike, Guduchi works by nourishing the immune system (immunomodulation). It enhances the production of macrophages—cells that engulf and digest pathogens. Furthermore, studies suggest it significantly lowers markers of oxidative stress, protecting your cells from damage that leads to premature aging and chronic disease.
Natural Food Sources
False Calumba is a specific medicinal herb and is not found in common fruits or vegetables. It is typically consumed as a powder, juice, or capsule derived directly from the stem.
Supplementation
Dosage:
- Powder (Churna): 1–3 grams twice daily.
- Extract: 300–600 mg daily (standardized to contain 2-5% bitter principles). Best Time: Morning on an empty stomach or before meals to aid digestion and immunity. Who Should Take It: Individuals with frequent infections, those recovering from illness, people with high stress levels, or anyone seeking natural liver support.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety Profile
False Calumba is generally considered safe for most people when taken at recommended doses for short periods (up to 8 weeks).
Side Effects:
- Dry mouth
- Increased bowel movements
- Lowered blood sugar (hypoglycemia)
Who Should Avoid/Consult a Doctor:
- Diabetics: It lowers blood sugar significantly; medication dosages may need adjustment.
- Autoimmune Conditions: Because it boosts immune activity, it may worsen conditions like Lupus or MS.
- Pregnancy: Insufficient safety data exists; avoid use.
- Surgery: Stop taking at least 2 weeks before surgery due to blood sugar effects.
Scientific References
- [1]Upadhyay, A. K., et al. (2010). "Tinospora cordifolia: A review of its phytochemistry and clinical relevance." *Journal of Ethnopharmacology*.
- [2]Bairwa, K., et al. (2012). "Review on phytochemical and pharmacological properties of Tinospora cordifolia." *Indian Journal of Natural Products and Resources*.
- [3]Singh, S. S., et al. (2003). "Tinospora cordifolia: Morphology, phytochemistry and pharmacology." *Journal of Ethnopharmacology*.