Fucose

Bio-Activity Analysis
Fucose Bioavailability: Food vs. Supplement
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Boosts Immune Defense: Helps your body recognize and fight off harmful bacteria and viruses.
- Supports Gut Health: Feeds beneficial gut bacteria and protects the gut lining.
- Promotes Healthy Aging: May help maintain cognitive function and cellular repair.
Deep Dive
Fucose is primarily involved in a process called fucosylation. This is a fancy word for attaching fucose molecules to proteins on the surface of your cells. This mechanism is critical for cell-to-cell communication. For your immune system, this means your white blood cells can better identify which cells are 'self' versus foreign invaders. Additionally, fucose acts as a prebiotic, feeding specific beneficial bacteria in your gut like Akkermansia muciniphila, which is linked to better metabolic health and a stronger gut barrier.
Natural Food Sources
Fucose is naturally present in various plants and sea vegetables. While it's most concentrated in human milk (where levels are highest during the first months of nursing), adults can obtain it from a diet rich in seaweed and specific fruits.
| Food | Amount | % DV |
|---|---|---|
| Wakame (Seaweed) | ~200mg per 100g | High |
| Sea Lettuce | ~150mg per 100g | High |
| Kombu (Kelp) | ~100mg per 100g | Medium |
| Blood Orange | ~50mg per 100g | Low |
| Carrots | ~30mg per 100g | Low |
Supplementation
When to supplement: If you do not eat seaweed or specific fruits regularly, or if you are looking for targeted immune support, a Fucose supplement (often derived from sea cucumber or Larch Arabinogalactan) is a viable option.
Dosage: There is no official RDA for Fucose. Clinical studies generally suggest a range of 500mg to 2000mg per day. It is best taken with food to improve absorption.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety Profile
Fucose is generally recognized as safe. Because it is a natural component of many foods and human milk, toxicity is extremely rare.
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Side Effects: Mild digestive upset (gas or bloating) can occur if you start with a high dose.
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Interactions: There are no known major drug interactions, but because it influences blood sugar levels slightly, those on medication for diabetes should monitor their glucose closely.
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Who should avoid it: There is limited data on Fucose during pregnancy or breastfeeding outside of its natural presence in food. Consult a doctor before taking concentrated supplements in these cases.
Scientific References
- [1]Bi, S., & Huang, W. (2019). L-Fucose and Fucosylated Oligosaccharides: Potential Health Benefits.
- [2]Pickard, J. M., et al. (2017). Gut fungi and fucose metabolism.
- [3]National Institutes of Health (NIH) - Dietary Supplements Fact Sheets.