Hematoporphyrin

Bio-Activity Analysis
Porphyrin Concentration in Common Foods
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Cellular Defense: Acts as an antioxidant, helping to neutralize free radicals that damage cells.
- Photosensitization: Used medically to increase sensitivity to light, which can help in specific therapeutic treatments (like targeting abnormal cells).
- Energy Production: As a precursor to heme, it supports the body's natural processes in creating healthy blood cells.
Deep Dive
Hematoporphyrin is structurally similar to hemoglobin, the oxygen carrier in your red blood cells. Its primary mechanism involves interacting with light and oxygen. In the context of dietary supplements, it is often marketed for its ability to support the body's natural oxidative stress response. When exposed to specific wavelengths of light, hematoporphyrin can produce reactive oxygen species, a mechanism that, while primarily used in clinical settings for photodynamic therapy, suggests a high level of bioactive potential. For the everyday user, it contributes to the pool of porphyrins essential for mitochondrial function and cellular energy.
Natural Food Sources
While you won't find 'pure' hematoporphyrin in a salad, you can consume its precursor molecules (porphyrins and chlorophyll) which the body utilizes. Plant-based diets are the richest natural source.
| Food | Amount | % DV |
|---|---|---|
| Spinach (Raw) | 1 cup | High (Chlorophyll source) |
| Parsley | 1/4 cup | High (Chlorophyll source) |
| Beef Liver | 3 oz | Moderate (Heme source) |
| Red Meat | 3 oz | Moderate (Heme source) |
| Lentils | 1 cup | Low-Moderate |
Supplementation
Hematoporphyrin is often found in liquid drops or softgels, typically derived from porcine (pig) liver extracts or synthesized. It is usually taken at doses of 10–30 mg per day. Because it acts as a photosensitizer, it is often taken in cycles rather than daily year-round. Always take with a meal containing fat to aid absorption.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety & Interactions
CRITICAL WARNING: Hematoporphyrin is a photosensitizer. This means it makes your skin and eyes extremely sensitive to sunlight. While taking this supplement, you must avoid direct sunlight and UV rays to prevent severe burns or eye damage.
Who should avoid it:
- Individuals with Porphyria (a rare genetic disorder affecting heme production).
- Pregnant or breastfeeding women (insufficient safety data).
- Those taking tetracyclines or fluoroquinolone antibiotics (increased photosensitivity).
Side Effects:
- Nausea or stomach cramps.
- Skin redness or itching when exposed to light.
- Darkening of urine.
Scientific References
- [1]Porphyrins as photosensitizers in photodynamic therapy. *Journal of Photochemistry and Photobiology*.
- [2]The role of porphyrins in cellular respiration and oxidative stress. *Free Radical Biology and Medicine*.
- [3]Clinical applications of hematoporphyrin derivative in oncology. *Lasers in Medical Science*.