Heneicosapentaenoic acid

Why You Need It

• Balances Inflammation: Unlike common omega-6s that can spark inflammation, HPA helps produce molecules that resolve inflammation, keeping your body in a state of healthy equilibrium.
• Supports Brain Health: It contributes to the structural integrity of brain cell membranes, facilitating clear communication between neurons for better focus and memory.
• Promotes Metabolic Wellness: Early research suggests HPA plays a role in regulating glucose and lipid metabolism, supporting a healthy weight and energy levels.

Deep Dive

Heneicosapentaenoic acid (HPA) is a specialist in the lipid world. While most dietary omega-6s (like linoleic acid) are pro-inflammatory, HPA acts differently. It competes with arachidonic acid (a highly inflammatory omega-6) for space in your cell membranes. By taking its place, HPA reduces the production of inflammatory compounds and increases the production of resolvins and protectins—molecules that actively 'resolve' inflammation. This makes it a unique ally for joint comfort, cardiovascular health, and preventing chronic low-grade inflammation. It is particularly concentrated in the retina and brain, suggesting a vital role in visual processing and cognitive longevity.

Natural Food Sources

HPA is not found in common fruits or vegetables. It is primarily sourced from specific marine life and rare plant oils.

Supplementation

Because HPA is difficult to obtain from a standard diet, supplementation is the most practical way to increase intake. Look for specialized marine oil supplements or high-grade evening primrose oil blends. Typical dosages in research range from 500mg to 2g daily, but always follow the manufacturer's instructions or a doctor's advice. This is particularly relevant for individuals seeking non-inflammatory fatty acid support without relying solely on fish oil.