Health Guide

Inositol Citrulline Silicate

Inositol Citrulline Silicate is a unique, patented compound often marketed as a 'trace mineral transporter.' It combines three essential components: Inositol (a sugar-alcohol often grouped with Vitamin B), Citrulline (an amino acid found in watermelon), and Silicate (mineral silica). Think of it as a high-tech delivery system designed by nature. The Inositol and Citrulline act as 'carriers' to help transport Silicate (essential for collagen and bone health) through the gut and into your bloodstream much more efficiently than taking silica alone. It is a specialized ingredient, typically found in premium bone and beauty supplements.
Evidence BasedDietary Supplement
Inositol Citrulline Silicate
VERIFIED SOURCE

Bio-Activity Analysis

Silica Bioavailability Comparison

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Absorption Rate (%)
Source Type

Health Benefits & Sources

Why You Need It

  • Enhanced Silica Absorption: It bypasses the body's natural filtration to deliver silica directly where it's needed.
  • Bone Density Support: Helps stimulate osteoblasts (bone-building cells) for stronger bones.
  • Connective Tissue Strength: Essential for collagen synthesis, improving skin elasticity, hair strength, and joint health.

Deep Dive

Most of us consume silica (from bananas, oats, green beans), but our bodies struggle to absorb it—often excreting over 90% of it. This is where Inositol Citrulline Silicate (ICS) shines. The Citrulline component converts to Arginine in the body, which improves blood flow. This increased circulation, combined with the carrier effect of Inositol, ensures the Silicate mineral actually reaches your cells. For you, this means better structural health without needing to consume massive amounts of plant matter. It is particularly effective for post-menopausal women looking to maintain bone density naturally.

Natural Food Sources

While you cannot eat a banana or drink watermelon juice to get this specific compound, you can get the raw building blocks. The body creates Inositol from the foods we eat, and Citrulline is abundant in certain fruits. Silica is found in fibrous plants.

Food SourceTypeBenefit
WatermelonFruitHighest natural source of Citrulline.
BananasFruitGood source of Inositol and Potassium.
OatsGrainRich in natural Silica (orthosilicic acid).
CucumbersVegetableHigh in Silica (skin is best).

Supplementation

Because ICS is a patented laboratory-synthesized compound designed for high bioavailability, it is not found naturally in food. You will find it listed as an ingredient in specialized bone health or 'beauty from within' supplements. If you are looking for the raw components, you can supplement generic L-Citrulline, Inositol powder, or Bamboo Silica separately, though the absorption synergy will be different.

Top Food Sources

Watermelon
Best natural source for the amino acid component.
Oats / Barley
Key for natural mineral intake.
Bananas
Contains the sugar-alcohol carrier.
Spinach
Leafy greens provide trace minerals.
Cucumbers
Eat with skin on for max benefit.

Frequently Asked Questions

It is a semi-synthetic compound. While the ingredients (Inositol, Citrulline, Silicate) occur naturally in food, this specific bonded form is created in a lab to ensure it survives digestion and enters the bloodstream efficiently.
Collagen is the protein structure. Silicate (Silica) acts as the 'glue' or scaffolding that helps your body *build* and stabilize that collagen. You need silica to utilize the collagen you eat or synthesize.
You would need to eat a very large amount of watermelon (approx. 1-2 kg) to get the equivalent of a clinical dose of Citrulline. However, eating watermelon is great for general hydration and mild nitric oxide boost.
It may help with hair *quality* (strength, thickness) due to silica's role in follicle health. It is not a cure for genetic pattern baldness, but it can improve the structural integrity of existing hair.

Safety & Side Effects

Inositol Citrulline Silicate is generally considered safe for healthy adults as it is a mineral carrier.

Who should avoid it?

  • Kidney Issues: If you have a history of kidney stones or severe kidney disease, consult a doctor. While Silicate is generally safe, high mineral intake can stress compromised kidneys.
  • Pregnancy/Breastfeeding: Safety data is limited for this specific patented form; stick to standard prenatal vitamins unless advised by a physician.
  • Medication Interactions: Citrulline can lower blood pressure. If you take blood pressure medication (nitrates, alpha-blockers), monitor your levels closely to avoid hypotension (dizziness/fainting).

Scientific References

  • [1]Calomme, M., et al. (1992). 'Absorption of orthosilicic acid and its effects on collagen synthesis.' *Biological Trace Element Research*.
  • [2]Bender, D. A. (2003). 'Nutritional Biochemistry of the Vitamins.' *Cambridge University Press* (Inositol and Citrulline pathways).
  • [3]Jugdaohsingh, R., et al. (2002). 'Dietary silicon intake and absorption.' *American Journal of Clinical Nutrition*.