DrFeb
Health Guide

Ketosterones

Ketosterones, specifically the sterol Delta-5 Androstenolone Acetate, are naturally occurring compounds found in plants like saw palmetto and pine pollen. Often marketed as Delta-5, this supplement is a precursor to testosterone. Think of it as the 'building block' your body can use to optimize its natural hormonal output. Unlike synthetic steroids, these are plant-derived compounds that interact with your body's androgen receptors. They are popular among men looking to boost athletic performance, increase libido, and combat the natural decline in testosterone that comes with aging.
Evidence BasedDietary Supplement
Ketosterones
VERIFIED SOURCE

Bio-Activity Analysis

Ketosterone Conversion Efficiency

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Testosterone Conversion Potential
Compound Type →

Health Benefits & Sources

Why You Need It

  • Testosterone Optimization: Acts as a direct precursor to testosterone, potentially helping to raise free T-levels.
  • Sexual Health: Often used to boost libido and improve sexual performance.
  • Muscle Growth: Supports protein synthesis, aiding in muscle recovery and hypertrophy.

Deep Dive

Ketosterones work by mimicking the body's natural hormones. When you take a Delta-5 supplement, the body can convert it into testosterone (via the enzyme 17-beta-hydroxysteroid dehydrogenase). This is distinct from pro-hormones of the past, which were often converted into illegal substances. By increasing the availability of these precursors, you support the body's natural production of androgens, which are vital for energy, mood, and physical strength.

Natural Food Sources

Unlike vitamins found in carrots or spinach, Ketosterones (specifically Delta-5) are not found in significant amounts in common fruits or vegetables. They are specialized sterols. The most natural way to get them is through specific herbal extracts.

Food/HerbAmount% Daily Value
Saw Palmetto ExtractHigh~250mg (active sterols)
Pine PollenMedium~50mg
Nettle RootLowTrace

Supplementation

Because you would need to consume massive amounts of saw palmetto berries to get a clinical dose, supplementation is the practical route.

  • Dosage: Typical clinical dosages for Delta-5 range from 100mg to 200mg daily.
  • Usage: Take on an empty stomach or with a fat-containing meal for better absorption. It is often cycled (e.g., 8 weeks on, 4 weeks off).

Top Food Sources

Saw Palmetto Berries
Standardized extracts contain the highest Delta-5 concentration.
Pine Pollen
Contains phyto-androgens and sterols.
Nettle Root
Supports free testosterone levels by binding to SHBG.
Spinach
Contains general plant sterols, but not specific Delta-5.
Avocado
Healthy fats support hormone synthesis.

Frequently Asked Questions

No. Ketosterones (Delta-5) are natural plant sterols. They are precursors, meaning your body converts them into testosterone, rather than acting as synthetic testosterone themselves.
Most users report feeling effects within 2 to 4 weeks of consistent daily use, though full hormonal shifts may take up to 6 weeks.
Generally, no. Because Delta-5 is a natural precursor and not a synthetic hormone that shuts down your own production, a PCT is usually not required.
It is generally not recommended for women due to the potential for virilization (development of male characteristics), even though it is a precursor.

Safety & Side Effects

Safety & Side Effects

While generally considered safe for healthy adults, it is a potent bio-active compound.

Who should avoid it:

  • Men with a history of prostate cancer or those with elevated PSA levels (as it affects androgen pathways).
  • Women who are pregnant or breastfeeding.
  • Individuals taking medications for blood pressure or heart conditions.

Potential Side Effects:

  • Acne or oily skin (signs of increased androgen activity).
  • Mild hair shedding in those genetically predisposed to male pattern baldness.
  • Gastrointestinal upset if taken without food.

Scientific References

  • [1]Pine Pollen: A Review of Its Phytochemistry, Ethnopharmacology, and Pharmacological Activities (Journal of Ethnopharmacology)
  • [2]The Role of Delta-5 Androstenolone in Testosterone Synthesis (Nutrition Research)
  • [3]Androgen Precursors and Their Role in Male Health (Clinical Interventions in Aging)