Khella

Bio-Activity Analysis
Khella's Effect on Smooth Muscle
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Relaxes Airways: Helps open up bronchial tubes, making breathing easier.
- Eases Kidney Stones: Assists in passing kidney stones by relaxing the ureter.
- Supports Vascular Health: Can help dilate blood vessels, improving blood flow.
- Anti-Spasmodic: Calms muscle cramps and spasms in the gut or bladder.
Deep Dive
Khella works primarily through its active compound, khellin. This substance inhibits calcium channels in smooth muscle cells. Simply put, calcium triggers muscle contraction; by blocking some of that calcium, Khella allows the muscles to relax. This is why it is effective for conditions like asthma (relaxing airways) and kidney stones (relaxing the tubes the stones travel through). Historically, it was even used before modern inhalers to manage asthma attacks.
Natural Food Sources
Khella is an herbal supplement derived from the seeds of the Ammi visnaga plant. It is not found in common fruits or vegetables. It is consumed as a tea, tincture, or dried extract.
Supplementation
- Dosage: Typically 100–200mg of dried extract daily, or 1 cup of seed tea.
- Who should take it: Individuals with mild asthma or those prone to kidney stones (under medical supervision).
- Best time to take: It acts quickly; take it when symptoms arise or to aid in stone passage.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Khella increases photosensitivity (sensitivity to sunlight). Long-term use or high doses can lead to liver issues. It may interact with medications metabolized by the liver (CYP3A4 substrates). Avoid if you have liver disease or are pregnant. Always consult a doctor before using Khella, especially if you are taking prescription medications.
Scientific References
- [1]Thompson, P. J., & Mitchell, D. M. (1982). 'Khellin in the treatment of asthma.' *Thorax*.
- [2]Al-Khawajah, M. M. (1997). 'Khellin and ureteric colic.' *British Journal of Urology*.
- [3]National Center for Complementary and Integrative Health (NCCIH) - Herbal Medicine Database.