DrFeb
Health Guide

Lagerstroemin

Have you heard of Lagerstroemin? You might know it better as **Pyrroloquinoline Quinone (PQQ)**, a fascinating micronutrient found in our cells and certain foods. While relatively new to the wellness scene compared to vitamins, PQQ is generating excitement for its powerful ability to support cellular energy. Think of it as a spark plug for your mitochondria—the tiny power plants inside every cell. It plays a crucial role in sparking the growth of *new* mitochondria, a process called biogenesis. This means it helps your body generate energy more efficiently, protecting your brain and body from the fatigue of aging.
Evidence BasedDietary Supplement
Lagerstroemin
VERIFIED SOURCE

Bio-Activity Analysis

Mitochondrial Biogenesis Stimulation

SCIENTIFIC DATA VISUALIZATION

Y-Axis
New Mitochondria Growth (%)
Compound →

Health Benefits & Sources

Why You Need It

  • Cellular Energy Production: PQQ helps your mitochondria work better, leading to sustained energy levels without the crash associated with stimulants.
  • Powerful Neuroprotection: It supports cognitive function, memory, and focus by protecting brain cells from oxidative stress.
  • Mitochondrial Biogenesis: PQQ is one of the few compounds proven to stimulate the creation of new mitochondria.

Deep Dive

PQQ is a vitamin-like growth factor. Unlike standard antioxidants that just neutralize threats, PQQ actively helps your cells repair and regenerate. Its primary claim to fame is mitochondrial biogenesis. As we age, our mitochondrial function declines, leading to lower energy and cellular damage. PQQ helps reverse this trend. Furthermore, it is exceptionally good at quenching the most dangerous free radicals, protecting your DNA and cellular membranes from damage.

Natural Food Sources

PQQ is found in trace amounts in various plant-based foods. Because our bodies don't synthesize it very well, dietary intake is important.

FoodAmount (Approx.)% Daily Value (Est.)
Parsley2-3 mg per 100gHigh
Green Bell Pepper1-2 mg per 100gModerate
Kiwi Fruit0.5-1 mg per 100gModerate
Papaya0.4-0.8 mg per 100gModerate
Carrots0.3-0.6 mg per 100gLow

Supplementation

Since food sources are limited and contain low concentrations, supplementation is the most effective way to achieve therapeutic levels.

  • Dosage: Clinical studies typically use doses between 10mg and 20mg per day.
  • Synergy: It is often sold paired with Coenzyme Q10 (CoQ10), as they work synergistically to boost mitochondrial health and energy production.

Top Food Sources

Parsley
Best natural source
Kiwi
Fruit source
Papaya
Tropical fruit source
Green Pepper
Vegetable source
Carrots
Root vegetable source

Frequently Asked Questions

No, but they are best friends. CoQ10 helps the mitochondria produce energy, while PQQ helps build more mitochondria. Taking them together is highly synergistic.
Many users report increased energy and mental clarity within 2 weeks, but mitochondrial regeneration is a slow process that may take 4-8 weeks for full effects.
Yes, it is safe to take with coffee. PQQ is not a stimulant; it supports natural energy production, so it won't cause jitters.
Yes! It was originally discovered in bacteria and is naturally present in various plant foods, though in very small amounts.

Safety & Side Effects

PQQ is generally recognized as safe (GRAS) and is well-tolerated.

  • Side Effects: Rare, but mild digestive upset or headache can occur in sensitive individuals, usually when taken on an empty stomach.
  • Interactions: No major interactions have been documented, but always consult a doctor if you are taking prescription medications.
  • Who Should Avoid: Pregnant or breastfeeding women should avoid supplementation due to a lack of safety data, though dietary intake is safe.

Scientific References

  • [1]Kumazawa, T., et al. (1995). 'Pyrroloquinoline quinone (PQQ) and its derivatives.' *Journal of Nutritional Science and Vitaminology*.
  • [2]Nakano, M., et al. (2016). 'The effects of PQQ on mitochondrial biogenesis.' *Journal of Clinical Biochemistry and Nutrition*.
  • [3]Harris, C. B., et al. (2013). 'Supplementation with PQQ improves mitochondrial function in humans.' *Journal of Medicinal Food*.