Leucyl-L-Isoleucine

Why You Need It

• Stabilizes Blood Sugar: Helps improve insulin sensitivity, keeping your energy levels steady.
• Prevents Muscle Breakdown: Protects your hard-earned muscle tissue during calorie restriction or heavy training.
• Boosts Fat Burning: Encourages the body to use fat stores for energy (lipolysis).

Deep Dive

Leucine and Isoleucine are two of the three essential Branched-Chain Amino Acids. When combined as Leucyl-L-Isoleucine, they work synergistically. Leucine is the primary 'trigger' for Muscle Protein Synthesis (MPS)—essentially telling your body to build muscle. Isoleucine, however, is the key regulator of glucose uptake. It helps your muscles pull sugar from the blood to use as fuel. By taking them together in this specific ratio, you get the dual benefit of muscle repair and metabolic control. This is particularly useful for those on a low-carb diet or athletes training in a fasted state.

Natural Food Sources

While you can find BCAAs in most protein-rich foods, Leucyl-L-Isoleucine is technically a peptide bond found within whole proteins. To get this specific amino acid pair, you must consume high-quality protein.

Supplementation

Because extracting this specific bond requires hydrolysis, it is most commonly found in supplement form.

• Dosage: Common dosages range from 2g to 5g taken 30 minutes before exercise.
• Who should take it: Endurance athletes, bodybuilders, or individuals managing blood sugar levels who struggle to get enough protein through diet alone.