Manganese picolinate

Bio-Activity Analysis
Manganese Absorption Efficiency
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Supports Metabolism: Helps activate enzymes needed to process cholesterol and carbohydrates.
- Bone Health: Essential for the formation of bone tissue and density.
- Antioxidant Defense: Aids in the production of superoxide dismutase (SOD), a powerful antioxidant that fights cellular damage.
- Wound Healing: Plays a role in collagen production, which is vital for skin repair.
Deep Dive
Manganese is a crucial component of the antioxidant enzyme superoxide dismutase (SOD). In simple terms, SOD acts as your body's first line of defense against free radicals—unstable molecules that can cause aging and inflammation. Without adequate manganese, your antioxidant defenses weaken. Furthermore, manganese picolinate is particularly useful for those concerned with nutrient absorption. Because it is chelated (bound) to picolinic acid, it bypasses standard absorption barriers in the gut, making it a preferred choice for individuals with digestive issues who struggle to uptake minerals from regular food or cheaper supplements.
Natural Food Sources
While supplements are helpful, nature provides the best synergy. Aim for whole foods first.
| Food | Amount | % DV |
|---|---|---|
| Pecans | 1.3 mg | 65% |
| Brown Rice (Cooked) | 0.9 mg | 45% |
| Spinach (Boiled) | 0.8 mg | 40% |
| Pineapple | 0.8 mg | 40% |
| Chickpeas | 0.6 mg | 30% |
Supplementation
Dosage: The Recommended Dietary Allowance (RDA) for adults is 2.3 mg (men) and 1.8 mg (women) daily. Supplements typically range from 5 mg to 20 mg per capsule.
Who Should Take It:
- Individuals with poor bone density.
- Those on restrictive diets lacking whole grains or nuts.
- People taking other chelated minerals (like zinc picolinate) for better absorption synergy.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety First
Manganese is safe in appropriate amounts, but because it is a heavy metal, toxicity is a concern with high-dose supplementation.
Side Effects: Excessive intake (usually above 11mg/day from supplements) can cause neurological symptoms similar to Parkinson's disease, such as tremors or muscle stiffness.
Who Should Avoid:
- Individuals with liver failure (the liver regulates manganese excretion).
- Those with iron-deficiency anemia (high manganese competes with iron for absorption).
Interactions: Avoid taking manganese supplements at the same time as antacids or calcium supplements, as these can reduce manganese absorption.
Scientific References
- [1]Manganese: Fact Sheet for Health Professionals (NIH Office of Dietary Supplements)
- [2]Klimis-Tavantzis, D. J. (Ed.). (1994). Manganese in Health and Disease. CRC Press.
- [3]Ascherio, A., et al. (1996). 'Manganese Intake in Relation to Parkinson's Disease.' Neurology.