N-Benzyl-Alpha-Phenylethylamine

Bio-Activity Analysis
N-Benzyl-PEA Bioavailability vs. Breakdown
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Mood Elevation: It acts as a releasing agent for dopamine and norepinephrine, potentially creating feelings of well-being.
- Cognitive Focus: Increases norepinephrine, which may help with alertness and concentration.
- Weight Management: Often used in 'fat burner' stacks due to its potential to increase metabolic rate.
Deep Dive
N-Benzyl-PEA is a trace amine and a structural analog of Phenylethylamine. In the body, it functions by interacting with trace amine-associated receptors (TAARs). This interaction stimulates the release of dopamine and norepinephrine from storage vesicles in the brain.
Why does this matter? Dopamine is the 'reward' neurotransmitter, while norepinephrine is responsible for the 'fight or flight' energy response. This combination can lead to a short-lived burst of energy, improved mood, and sharper focus. However, unlike its parent compound (PEA), the addition of the benzyl group may help it resist breakdown by enzymes (like MAO-B), potentially making it last longer in the body. It is important to note that effects are often subtle and highly dependent on individual brain chemistry.
Natural Food Sources
While N-Benzyl-PEA is primarily a synthetic compound used in supplements, it is chemically related to compounds found in nature. It is most commonly associated with the fermentation process found in certain foods.
| Food | Amount | % DV |
|---|---|---|
| Raw Cacao Beans | Trace | <1% |
| Fermented Foods | Trace | <1% |
| Chocolate (Dark) | Trace | <1% |
| Kefir/Yogurt | Trace | <1% |
| Red Wine | Trace | <1% |
Supplementation
Because natural dietary intake is negligible, N-Benzyl-PEA is almost exclusively taken as a supplement.
- Typical Dosage: Dosages in studies and supplements vary widely, typically ranging from 200mg to 500mg per day.
- Who Should Take It: It is generally used by individuals looking for a non-stimulant mood boost or a metabolic aid.
- Important Note: It is often stacked with other ingredients (like Green Tea Extract) to enhance bioavailability.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety Profile
Is it safe? While it is not a controlled substance, N-Benzyl-PEA is a potent chemical. It should be treated with respect.
- Side Effects: High doses may cause heart palpitations, anxiety, restlessness, rapid heart rate, or headaches.
- Interactions: It interacts with MAO inhibitors (MAOIs). Do not take this if you are on prescription antidepressants.
- Contraindications: Individuals with heart conditions, high blood pressure, or anxiety disorders should avoid this compound.
- Dependency: There is a risk of tolerance (needing more to feel the same effect) if taken daily. Cycling (taking breaks) is highly recommended.
Scientific References
- [1]Burchett, S. A., & Hicks, T. P. (2006). The mysterious trace amines: potent neuromodulators of the CNS. *Progress in Neurobiology*.
- [2]Berry, M. D. (2007). The potential of trace amines for the treatment of mood disorders. *CNS Drugs*.
- [3]Premont, R. T. (2009). The TAAR receptor family: a new class of neuromodulatory targets. *Neuropharmacology*.