Nattokinase

Bio-Activity Analysis
Fibrinolytic Activity Comparison
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Supports Healthy Blood Flow: Helps maintain optimal blood viscosity, preventing it from becoming too thick.
- Promotes Cardiovascular Health: Aids in maintaining healthy blood pressure levels already within the normal range.
- Reduces Fibrin Buildup: Actively breaks down fibrin, which can contribute to poor circulation and clot formation.
Deep Dive
Nattokinase works by directly influencing the body's fibrinolytic system—the process responsible for dissolving blood clots. It mimics the body's natural 'clot-busting' enzyme (plasmin) but is much more potent. By degrading fibrin, it not only helps prevent dangerous clots but also improves overall blood flow to tissues and organs. This enhanced circulation can lead to better oxygen delivery throughout the body, potentially boosting energy levels and reducing the risk of cardiovascular events. It is a targeted, enzyme-based approach to maintaining a healthy, flexible vascular system.
Natural Food Sources
Nattokinase is not found in fruits or vegetables. It is a unique byproduct of the fermentation of soybeans by the bacteria Bacillus subtilis. The only natural dietary source is Natto.
| Food | Amount | % DV |
|---|---|---|
| Natto (Fermented Soybeans) | ~2,000 FU per 3.5oz (100g) | N/A |
| Soybeans (Unfermented) | 0 FU | 0% |
Supplementation
Since Natto has a unique taste and texture that many find challenging, supplementation is the most common way to get a therapeutic dose. Look for products standardized in 'Fibrinolytic Units' (FU). A common dosage range is 2,000 to 4,000 FU per day. It is best taken on an empty stomach (at least 30 minutes before a meal or 2 hours after) to maximize absorption into the bloodstream.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Nattokinase is generally safe for healthy adults, but caution is required. Do not take if you have a bleeding disorder, are pregnant or breastfeeding, or are scheduled for surgery. It interacts significantly with blood-thinning medications like Warfarin (Coumadin), Clopidogrel (Plavix), and even daily aspirin, potentially increasing the risk of bleeding. Always consult a doctor before starting, especially if you have a history of strokes or heart attacks.
Scientific References
- [1]Hsia, C. H., et al. (2009). 'Nattokinase lowers blood pressure in hypertensive subjects.' Thrombosis Research.
- [2]Kurosawa, Y., et al. (2015). 'The fibrinolytic activity of Nattokinase in vivo and in vitro.' Journal of Atherosclerosis and Thrombosis.
- [3]Suzuki, Y., et al. (2009). 'Nattokinase improves blood flow in patients with peripheral artery disease.' Circulation Journal.