Neoandrographolides

Why You Need It

• Inflammation Tamer: Helps reduce chronic inflammation markers naturally.
• Liver Guardian: Supports detoxification pathways and protects liver cells.
• Metabolic Balance: Aids in regulating glucose and lipid levels.
• Immune Modulator: Helps prime the immune system to respond faster to threats.

Deep Dive

Neoandrographolides function by interacting with key signaling pathways in the body, specifically the NF-κB pathway, which is the master switch for inflammation. By keeping this switch in check, they prevent the body from overreacting to stressors. Research suggests they are particularly effective in supporting liver health, helping to regenerate tissue after exposure to toxins. Unlike simple immune boosters, they act as adaptogens, meaning they help balance the immune system—boosting it when underactive and calming it when overactive (as in autoimmune conditions).

Natural Food Sources

Unlike common vitamins, Neoandrographolides are specialized phytochemicals. They are not found in standard fruits or vegetables but are concentrated in specific medicinal herbs.

Supplementation

Since these compounds are bitter and rare in the diet, supplementation is the most practical route.

• Standardization: Look for supplements standardized to contain 10-20% total lactones.
• Dosage: Clinical studies typically use 300mg to 600mg of extract daily, split into two doses.
• Timing: Take with meals to aid absorption and minimize stomach upset.