Nobiletin

Why You Need It

• Metabolic Health & Weight Management: Nobiletin helps rev up your metabolism and may prevent the accumulation of body fat.
• Brain Protection: It acts as a neuroprotectant, potentially improving memory and shielding the brain from age-related decline.
• Anti-Inflammatory Power: It fights chronic inflammation, a root cause of many modern diseases.
• Heart Support: Early research suggests it helps maintain healthy cholesterol and blood sugar levels.

Deep Dive

Nobiletin works by activating specific pathways in your body, particularly AMPK (often called the body's 'metabolic master switch'). When AMPK is active, your body burns energy more efficiently and reduces fat storage. Regarding the brain, Nobiletin crosses the blood-brain barrier to reduce oxidative stress, which is crucial for preventing conditions like Alzheimer's. It is not a stimulant, meaning it supports energy levels naturally without the jitters associated with caffeine.

Natural Food Sources

Nobiletin is not found in the flesh (pulp) of fruit; it is concentrated in the peel and white pith. Eating the whole fruit (zest included) is the best way to get it naturally.

Supplementation

Dosage: Clinical studies typically use dosages ranging from 50mg to 500mg per day.

Usage: Because Nobiletin is fat-soluble, take it with a meal containing healthy fats (like avocado or olive oil) to maximize absorption. It is best taken in the morning to align with your body's natural circadian rhythms.