Polylysine
Bio-Activity Analysis
L-Lysine Bioavailability: Food vs. Supplements
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Supports Collagen Production: L-Lysine is essential for creating collagen, the protein that keeps your skin, bones, and joints healthy and strong.
- Boosts Immune Health: It plays a key role in the production of antibodies and enzymes that help your body fight off infections.
- Aids in Calcium Absorption: L-Lysine helps your body absorb calcium, which is vital for maintaining strong bones and preventing osteoporosis.
- Essential for Muscle Repair: As a building block of protein, it is crucial for repairing tissue and building muscle mass after exercise.
Deep Dive
L-Lysine is classified as an 'essential' amino acid, meaning you must get it from food or supplements. It is a precursor to carnitine, a substance that helps convert fatty acids into energy. This makes it important not just for structure, but for your body's energy metabolism as well. Research suggests that adequate lysine intake can help reduce the severity and frequency of cold sores (herpes simplex virus) by blocking arginine, another amino acid the virus needs to replicate.
Natural Food Sources
Getting L-Lysine from food is the best approach. Animal proteins are the richest sources, but plant-based options are available too.
| Food | Amount | % DV |
|---|---|---|
| Parmesan Cheese | 1 oz (28g) | 50% |
| Chicken Breast | 3 oz (85g) | 45% |
| Canned Tuna | 3 oz (85g) | 40% |
| Turkey Breast | 3 oz (85g) | 40% |
| Cod Fish | 3 oz (85g) | 35% |
| Pumpkin Seeds | 1 oz (28g) | 20% |
| Lentils | 1/2 cup cooked | 15% |
Supplementation
While most people get enough lysine from their diet, some may benefit from a supplement. A common dosage for general health is 1,000 mg per day. For specific therapeutic uses (like managing cold sores), dosages up to 3,000 mg per day may be used, but always under medical guidance. It is best absorbed when taken with a meal, preferably with carbohydrates to stimulate insulin release, which aids amino acid transport.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
L-Lysine is generally considered safe for most people when taken in appropriate doses. However, high doses (over 3,000 mg/day) can sometimes cause:
- Gastrointestinal upset: Stomach cramps, diarrhea, or nausea.
- Kidney issues: People with pre-existing kidney disease or high triglyceride levels should consult a doctor before supplementing.
- Pregnancy/Breastfeeding: Safe in normal dietary amounts, but supplement use should be discussed with a healthcare provider.
It is a naturally occurring nutrient, not a synthetic drug, but always treat supplements with respect.
Scientific References
- [1]Reeds, P. J. (2000). Dispensable and indispensable amino acids for humans. The Journal of Nutrition.
- [2]Griffith, R. S., et al. (1987). A controlled study of the effect of L-lysine monohydrochloride on the recurrence of herpes labialis. The Journal of Dermatology.
- [3]Civitelli, R., et al. (1992). Dietary L-lysine and calcium metabolism in humans. Nutrition.