Pyritinol

Bio-Activity Analysis
Brain Glucose Uptake Enhancement
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Might Need It
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Enhanced Cognitive Performance: Pyritinol is well-regarded for its ability to sharpen focus and mental clarity. It works by increasing glucose uptake in the brain, providing your neurons with more fuel.
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Memory Support: By promoting the release of acetylcholine (a key neurotransmitter for learning), it may help improve both short-term and long-term memory recall.
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Mood and Energy: Many users report a mild mood lift and reduced mental fatigue. It helps convert food into energy more efficiently within the brain.
Deep Dive
Pyritinol functions by stimulating the transport of glucose and oxygen across the blood-brain barrier. Think of it as upgrading the fuel lines to your brain's engine. It also plays a role in membrane fluidity, helping brain cells communicate faster. However, because it is a potent chemical form of B6, it is not a replacement for a healthy diet and should be treated with the respect due to a pharmaceutical agent.
Natural Food Sources
Important Note: Pyritinol is not found in nature. It is a synthetic compound created in a laboratory. However, it is derived from Vitamin B6. To support your brain naturally, you should focus on consuming foods rich in Pyridoxine (Vitamin B6).
| Food | Amount (per 100g) | % Daily Value (approx) |
|---|---|---|
| Chickpeas | 0.5 mg | 29% |
| Salmon | 0.4 mg | 24% |
| Potatoes | 0.3 mg | 18% |
| Bananas | 0.4 mg | 22% |
| Chicken Breast | 0.6 mg | 35% |
Supplementation
- Dosage: Clinical studies typically use 100mg to 200mg per day, divided into two doses (morning and early afternoon).
- Who should take it: This is generally for adults experiencing mental fatigue, difficulty concentrating, or age-related cognitive decline. It is popular among biohackers for performance enhancement.
- Cycling: It is highly recommended to cycle Pyritinol (e.g., 5 days on, 2 days off) to prevent tolerance and reduce side effects.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety & Side Effects
Because Pyritinol is a potent chemical derivative, it carries risks that standard supplements do not.
Who should avoid it:
- Individuals with a history of epilepsy or seizures (it may lower the seizure threshold).
- Those with kidney disease.
- Pregnant or breastfeeding women.
Potential Side Effects:
- Allergic Reactions: Pyritinol is known to cause allergic skin reactions (rashes, itching) in some people.
- Gastrointestinal Distress: Nausea and stomach pain are common.
- Headaches: Overdosing can lead to tension headaches.
Warning: Excessive intake over long periods can lead to peripheral neuropathy (nerve damage in hands and feet), similar to Vitamin B6 toxicity.
Scientific References
- [1]Kugler, P., et al. (1982). 'The effect of pyritinol on memory and mental performance in the elderly.' *Pharmakopsychiatrie Neuropsychopharmakologie*.
- [2]Bente, D., et al. (1978). 'Pyritinol: A review of its pharmacological and clinical properties.' *Arzneimittelforschung*.
- [3]National Institutes of Health (NIH) Office of Dietary Supplements: Vitamin B6 Fact Sheet for Health Professionals.