Health Guide

Sodium ferrocyanide

Let's talk about a compound that often confuses people: Sodium Ferrocyanide. You might know it by its food additive name, E535, or as Yellow Prussiate of Soda. Chemically, it is a coordination compound of sodium, iron, and cyanide. Now, I know what you are thinking—cyanide sounds dangerous! However, in this specific molecule, the cyanide groups are tightly locked onto the iron atom. This makes the compound incredibly stable and non-toxic to humans. Think of it like a locked box: the poison is inside, but the box is unbreakable in the human body. Its primary role in health and supplementation is actually for *safety*: it is a powerful anti-caking agent that keeps your salt and spices free-flowing and fresh.
Evidence BasedDietary Supplement
Sodium ferrocyanide
VERIFIED SOURCE

Bio-Activity Analysis

Stability of Cyanide in Ferrocyanide vs. Free Cyanide

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Toxicity Risk (Low to High)
Compound Type

Health Benefits & Sources

Why You Need It

  • Prevents Clumping: Keeps powdered supplements and spices flowing smoothly.
  • Ensures Iodine Intake: Essential for iodized salt to prevent clumping, which helps avoid iodine deficiency.
  • Stabilization: Stabilizes certain sensitive ingredients in fortified foods.

Deep Dive

Sodium Ferrocyanide is a flow agent. Imagine you have a container of salt or a powdered vitamin mix. Over time, humidity can cause the fine particles to stick together, forming hard rocks. This makes measuring accurate doses impossible. Sodium Ferrocyanide coats the tiny particles, creating a microscopic barrier that stops them from sticking. Because it is so stable, it passes through your digestive system unchanged. Your body absorbs the iron (if any is released, which is minimal), but the cyanide stays locked away, making it safe for consumption.

Natural Food Sources

Because Sodium Ferrocyanide is a synthetic additive created in a lab, it does not occur naturally in fruits, vegetables, or whole foods. You will only find it in processed salt, table salt, and certain spice blends. To get the benefits of 'cyanide' (in the safe form of Vitamin B17/Amygdalin), you would look at raw nuts like bitter almonds, or fruit pits (apricot kernels), though these carry their own safety warnings.

Supplementation

You generally do not need to supplement this specific chemical. It is already present in the iodized salt you likely use daily. If you are manufacturing your own supplements or spice blends at home and find they are clumping, adding a tiny amount of food-grade Sodium Ferrocyanide (E535) can help.

Typical Usage:

  • For table salt: Less than 0.005% by weight.
  • For powdered spices: Trace amounts (usually under 10mg per kg of product).

Top Food Sources

Iodized Table Salt
Less than 0.005% of product
Seasoning Blends
Found in powdered garlic/onion salts
Powdered Supplements
Used as a flow agent
Bitter Almonds
Contains natural cyanogenic compounds (different chemical)
Apple Seeds
Contains natural cyanogenic compounds (different chemical)

Frequently Asked Questions

No. While it contains cyanide groups, they are chemically bound to iron in a way that makes them non-toxic and unable to interact with the body's cells.
No. Because it passes through the body unabsorbed, it does not interfere with B12 absorption like free cyanide does.
Salt is very hygroscopic (absorbs water from the air). Without an anti-caking agent like this, your salt would turn into a solid brick.
Yes, at the trace amounts found in food, it is considered safe. However, always consult your doctor regarding dietary additives.

Safety & Side Effects

Sodium Ferrocyanide is considered 'Generally Recognized As Safe' (GRAS) by the FDA and EFSA. The human stomach is highly acidic, but even under these conditions, this compound does not break down to release free cyanide. It is excreted in the urine. However, people with severe kidney disease should consult a doctor before consuming large amounts of processed foods containing additives, as clearance mechanisms may be impaired.

Scientific References

  • [1]EFSA Panel on Food Additives and Nutrient Sources (ANS). Scientific Opinion on the re-evaluation of Sodium Ferrocyanide (E 535) as a food additive.
  • [2]U.S. Food and Drug Administration (FDA). Title 21 CFR Section 182.1775 - Sodium ferrocyanide.
  • [3]World Health Organization (WHO). Food Additive Series: Sodium Ferrocyanide.