Health Guide

Vincamine

Vinpocetine is a synthetic compound derived from thevincamine alkaloid found in the Periwinkle plant. It is a potent 'nootropic' (brain booster) that works by significantly increasing blood flow to the brain and improving the way brain cells utilize oxygen and glucose. While not naturally found in food, it mimics compounds found in nature to support memory, focus, and protect brain cells from aging and oxidative stress.
Evidence BasedDietary Supplement
Vincamine
VERIFIED SOURCE

Bio-Activity Analysis

Vinpocetine Absorption Rate

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Absorption Efficiency
Condition

Health Benefits & Sources

Why You Need It

  • Boosts Brain Blood Flow: Acts as a vasodilator specifically for cerebral vessels.
  • Enhances Memory & Focus: Supports the metabolic rate of brain cells.
  • Protects Neurons: Acts as an antioxidant to shield brain tissue from damage.

Deep Dive

Vinpocetine works on two fronts: circulation and metabolism. By increasing the elasticity of red blood cells, it allows for better micro-circulation in the brain's tiny capillaries. Simultaneously, it protects the brain's energy molecules (ATP) from being broken down too quickly. This dual action results in better short-term memory, faster information recall, and reduced 'brain fog.'

Natural Food Sources

Unlike vitamins found in fruits and vegetables, Vinpocetine is not present in the food supply. It is a synthesized derivative of the alkaloid Vincamine, which is extracted from the seeds of the Lesser Periwinkle (Vinca minor) plant.

Supplementation

  • Form: Usually found in 5mg or 10mg capsules.
  • Dosing: 10-30mg daily.
  • Crucial Tip: Always take with a meal containing carbohydrates. Vinpocetine is poorly absorbed alone but absorption increases by up to 300% when taken with sugar.

Top Food Sources

Lesser Periwinkle Seeds
Contains Vincamine (Precursor). Not for direct consumption.
Synthetic Supplement
Standardized to 5-10mg per capsule.

Frequently Asked Questions

Yes, it is a synthetic derivative of the vincamine alkaloid found in the Lesser Periwinkle (Vinca minor) plant.
It acts very quickly (within 30-60 minutes) due to its rapid absorption, but cognitive benefits typically require consistent daily use over several weeks.
Yes, many users stack it with caffeine for focus, but be mindful of blood pressure. Vinpocetine lowers blood pressure slightly.
Some older studies suggested it helps with tinnitus (ringing in the ears) caused by blood flow issues, though modern evidence is mixed.

Safety & Side Effects

WARNING: Vinpocetine thins the blood. Do not use if you are pregnant, breastfeeding, or have a bleeding disorder. Avoid taking with prescription blood thinners, aspirin, or ibuprofen. Discontinue use 2 weeks before surgery.

Scientific References

  • [1]Miskolczi, P., et al. (1995). 'Vinpocetine increases cerebral blood flow in healthy volunteers.'
  • [2]Patyar, S., et al. (2011). 'Pharmacology of Vinpocetine: A review.'
  • [3]Hadiev, T., et al. (2019). 'Vinpocetine protects brain cells during hypoxia.'