DrFeb
Health Guide

Zinc L-Carnosine

Imagine a specialized bodyguard for your stomach lining. That is essentially what **Zinc L-Carnosine** (often called Polaprezinc) is. Unlike standard zinc supplements, this unique compound bonds zinc to a small protein fragment called L-Carnosine. This specific pairing creates a 'slow-release' effect that allows it to coat and soothe the stomach gently. It is widely used in Japan for ulcer care and is gaining popularity globally for protecting the gut, healing the skin, and maintaining oral health. It is a functional supplement designed for targeted support, not just general nutrition.
Evidence BasedDietary Supplement
Zinc L-Carnosine
VERIFIED SOURCE

Bio-Activity Analysis

Gastric Mucosal Healing Rate (Zinc L-Carnosine vs. Placebo)

SCIENTIFIC DATA VISUALIZATION

Y-Axis
Healing Score (0-10)
Group →

Health Benefits & Sources

Why You Need It

  • Stomach Lining Protection: It creates a protective shield over the stomach and intestinal walls.
  • Soothes Occasional Heartburn: Helps reduce the burning sensation associated with acid reflux.
  • Accelerates Skin Healing: Used in wound dressings to speed up the repair of skin tissue.
  • Supports Gum Health: Reduces inflammation in the mouth and helps heal canker sores.

Deep Dive

Zinc L-Carnosine works via a 'time-release' mechanism. When you ingest it, the zinc and carnosine separate slowly in the acidic environment of the stomach. The zinc stimulates the repair of stomach tissue, while the carnosine acts as a buffer against excess acid. Unlike other forms of zinc that might irritate a sensitive stomach, this compound is specifically designed to be soothing. It helps maintain the mucosal barrier, which is your body's first line of defense against digestive distress.

Natural Food Sources

Zinc L-Carnosine is a synthetic compound and does not exist naturally in food. However, you can consume the two components separately to support your body's needs.

FoodAmount% DV
Beef (Cooked)3 oz45%
Pumpkin Seeds1 oz20%
Chickpeas1 cup18%
Cashews1 oz15%
Yogurt1 cup12%

Supplementation

Since you cannot eat this compound, supplementation is the only route.

  • Typical Dosage: 75mg to 150mg daily (often split into two doses).
  • Best Time: Take on an empty stomach 30 minutes before meals, or as directed by a doctor for specific ulcer treatment.

Top Food Sources

Zinc L-Carnosine
Only available via supplementation
Beef
Natural Zinc source
Pumpkin Seeds
Natural Zinc source
Shellfish
Natural Zinc source
Lentils
Plant-based Zinc source

Frequently Asked Questions

You can, but they serve different purposes. Regular Zinc (like Zinc Gluconate) is great for immune support. Zinc L-Carnosine is uniquely bonded to protect and repair the stomach lining. If you have a sensitive stomach or ulcers, stick to L-Carnosine.
Yes, the molecule is the same (beta-alanine + histidine). However, in this context, it is acting as a buffering agent for the stomach rather than a muscle fuel.
For stomach issues, many people feel soothing relief within a few days. For full mucosal repair, studies suggest a course of 4 to 8 weeks.
Zinc generally can cause nausea if taken on an empty stomach. However, Zinc L-Carnosine is specifically designed to be gentler. If nausea occurs, try taking it with a very small amount of food.

Safety & Side Effects

Safety Profile

Zinc L-Carnosine is generally recognized as safe and well-tolerated.

Potential Side Effects:

  • Mild nausea.
  • A metallic taste in the mouth.
  • Temporary changes in bowel movements.

Who Should Avoid/Consult a Doctor:

  • Pregnancy/Breastfeeding: Safety data is limited; consult an OB-GYN.
  • Kidney Disease: Since zinc is filtered by the kidneys, those with compromised kidney function should use caution.
  • Long-term use: Taking high doses of zinc for over 3 months can lead to copper deficiency. If taking long-term, consider a copper supplement.

Scientific References

  • [1]Hosada, K., et al. (1991). 'Effect of zinc L-carnosine on gastric mucosal injury.' *Journal of Clinical Biochemistry and Nutrition*.
  • [2]Matsukura, T., & Tanaka, H. (2000). 'Usefulness of polaprezinc (Zinc L-Carnosine) for NSAID-induced gastropathy.' *Digestive Diseases and Sciences*.
  • [3]Yoshikawa, T., et al. (2001). 'Effect of zinc L-carnosine on experimental gastric ulcers.' *Free Radical Research*.