Advanced Digestive Support
Brand: AXIS Nutrition
Dr. Feb's Analysis
Scientific Mechanism
Advanced Digestive Support utilizes two primary actives to promote gut homeostasis. CoreBiome (Tributyrin) is a butyrate precursor. At the cellular level, it delivers butyric acid to colonocytes, serving as a preferred energy source for intestinal cells. This supports the integrity of the gut barrier by nourishing epithelial tissue and regulating inflammatory pathways like NF-κB. Berberine is an alkaloid that influences cellular signaling. It activates AMP-activated protein kinase (AMPK), a key regulator of cellular energy metabolism. This activation helps modulate the gut microbiome composition and supports healthy glucose and lipid metabolism. Together, these ingredients work synergistically to maintain mucosal health and digestive balance.
Key Benefits
Key benefits include:
- Supports a balanced gut microbiome environment.
- Promotes healthy intestinal barrier function.
- Aids in maintaining regular digestive comfort.
- Supports healthy metabolic function via AMPK activation.
Usage & Safety
Dosage: Take 2 capsules daily as directed on the label. Best Practices: For optimal absorption, take with a meal containing dietary fat, as CoreBiome is lipid-based. Consistency is key; take at the same time daily. Safety Interactions: Consult a healthcare provider before use if you are pregnant, breastfeeding, taking prescription medications (e.g., CYP3A4 substrates), or have an ongoing medical condition. Not for use by individuals with difficulty swallowing.