Cascara Sagrada 350 mg
Brand: Dr. Clark Research Association Dr. Clark Zentrum
Dr. Feb's Analysis
Scientific Mechanism
The active ingredient, Cascara Sagrada (Rhamnus purshiana), contains potent compounds known as anthraquinone glycosides (such as cascarosides). At a cellular level, these compounds are not absorbed in the upper GI tract. Upon reaching the colon, gut bacteria metabolize them into active anthrones. These anthrones irritate the colonic mucosa and stimulate the myenteric plexus, significantly enhancing peristalsis (intestinal muscle contractions). This action increases water secretion into the bowel lumen, resulting in softer stool and facilitating bowel movement.
Key Benefits
Key benefits include:
- Stimulates natural bowel movements
- Relieves occasional constipation
- Increases water content in stools for easier passage
- Supports short-term digestive cleansing
Usage & Safety
Take 1 capsule daily, preferably at bedtime, to allow the supplement to work overnight. Do not use for more than 7 consecutive days, as long-term use can lead to dependency and electrolyte imbalances. Do not use if you have abdominal pain, diarrhea, or are pregnant/nursing. Consult a healthcare provider if you are taking prescription medications, specifically cardiac glycosides or diuretics, due to potential electrolyte interactions.




