D Complex 2,000 IU (50 mcg)
Brand: Swanson
Dr. Feb's Analysis
Scientific Mechanism
Swanson D Complex 2,000 IU (50 mcg) delivers a potent dose of Vitamin D, specifically formulated as a blend of D2 (Ergocalciferol) and D3 (Cholecalciferol). At the cellular level, Vitamin D is a secosteroid hormone precursor. Upon ingestion, it undergoes hydroxylation in the liver to 25-hydroxyvitamin D and subsequently in the kidneys to the active form, calcitriol. This active form binds to Vitamin D receptors (VDR) located in the nucleus of cells, particularly in the small intestine and bone. This binding regulates gene expression, facilitating the transcription of proteins involved in calcium transport (like calbindin). By enhancing intestinal absorption of dietary calcium and phosphorus, it ensures sufficient mineralization of the bone matrix, maintaining skeletal integrity and modulating immune cell differentiation.
Key Benefits
Key benefits include:
- Supports bone density and skeletal strength by optimizing calcium absorption.
- Modulates the immune system to enhance innate defense mechanisms.
- Contributes to the maintenance of normal muscle function.
- Promotes overall mood and cognitive health through neuroregulatory actions.
Usage & Safety
The recommended dosage is 1 capsule daily, taken with a meal containing fat to maximize absorption of this fat-soluble vitamin. Do not exceed the recommended dose. Consult a healthcare provider before use if you are pregnant, nursing, have a medical condition (especially kidney disease or hyperparathyroidism), or are taking thiazide diuretics or cardiac glycosides. Keep out of reach of children.
