SAM-e 400 mg
Brand: HBC Protocols
Adult (18 - 50 Years)S-adenosyl-Methionine Disulfate TosylateOther Combinations
Quality score
85/100
DSLD
74981
UPC
—
Form
Tablet or Pill
Serving size
1 Tablet(s)
See label
Net contents
60 Tablet(s)
Standard Pack
Top DV
Vitamins
Per serving
Directions
Directions For Use: Adults take 1 - 4 tablets daily or as directed by your physician.
NIH DSLD-backedSource links included
Updated: 2026-01-16
Dr. Feb's Analysis
Scientific Mechanism
SAM-e (S-Adenosyl-Methionine) is the primary methyl donor in your body, essential for synthesizing neurotransmitters like serotonin and dopamine, regulating mood. It also donates sulfur for cartilage maintenance. The inclusion of Vitamin B6, Vitamin B12, and Folic Acid acts as vital cofactors in the methylation cycle, enhancing the bioavailability and efficacy of SAM-e to support cellular health and homocysteine metabolism.
Key Benefits
Key benefits include:
- Mood and cognitive support
- Joint comfort and cartilage formation
- Liver function and cellular detoxification
- Enhanced methylation with B-vitamin cofactors
Usage & Safety
Take 1 tablet daily, preferably on an empty stomach. For optimal absorption, take 30 minutes before a meal. Do not exceed recommended dosage. Consult a physician if you have bipolar disorder or are taking antidepressants.
Daily value highlights
No daily values established.
Receipts
Frequently Asked Questions
What are the key benefits of SAM-e 400 mg?▼
It supports mood balance, joint health, and liver function by acting as a primary methyl donor and sulfur source.
How should I take this supplement?▼
Take 1 tablet daily on an empty stomach, ideally 30 minutes before eating.
Are there known allergens?▼
Yes, the product contains S-adenosyl-Methionine Disulfate Tosylate.
Is HBC Protocols a reputable brand?▼
Yes, HBC Protocols is listed in the NIH Dietary Supplement Label Database (DSLD).
SAM-e 400 mg
Quality 85/100 • DSLD 74981