Flavanones

Bio-Activity Analysis
Bioavailability: Whole Fruit vs. Isolated Supplement
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Heart Health Guardian: Helps keep your blood pressure in a healthy range.
- Circulation Booster: Supports the flexibility of your arteries, allowing blood to flow freely.
- Anti-Inflammatory: Calms systemic inflammation, which is the root cause of many chronic diseases.
- Allergy Helper: Early research suggests they may help stabilize cells that trigger allergic reactions.
Deep Dive
Flavanones (specifically hesperidin, naringin, and eriodictyol) are concentrated almost exclusively in citrus peels and pulp. Unlike other antioxidants that just scavenge free radicals, flavanones have a unique relationship with your vascular system. They help your body produce nitric oxide, a gas that signals your blood vessels to relax and widen. This process, called vasodilation, improves blood flow and reduces the strain on your heart. They also work synergistically with Vitamin C, enhancing the antioxidant capacity of your blood.
Natural Food Sources
Because flavanones are located in the peel and the white pith (albedo) of citrus fruits, eating the whole fruit is better than just drinking the juice. Juicing often removes the fiber and the highest concentration of these compounds.
| Food | Amount (Hesperidin/Naringin) | % Daily Value (Estimate) |
|---|---|---|
| Orange (Whole) | 44 mg per 100g | ~50% |
| Grapefruit (Pink) | 28 mg per 100g | ~30% |
| Lemon (Whole) | 20 mg per 100g | ~20% |
| Tomato (Skin) | 5 mg per 100g | ~5% |
Supplementation
If you dislike citrus or have a specific vascular condition (like chronic venous insufficiency), supplements are available. Look for "Citrus Bioflavonoids" or specific isolates like "Hesperidin" or "Naringin". Standard dosages in studies range from 250mg to 500mg daily.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Flavanones from food are considered extremely safe for everyone. For supplements, caution is advised for those on blood thinners (like Warfarin) as they can slightly alter how the liver processes these drugs. Additionally, grapefruit-derived flavanones can interact with statins and blood pressure medications. Always consult a doctor if you are taking prescription meds before starting a supplement regimen.
Scientific References
- [1]Benavente-García, O., & Castillo, J. (2008). Update on uses and properties of citrus flavonoids. *Journal of Agricultural and Food Chemistry*.
- [2]Slavin, J. L. (2012). Fiber and prebiotics: mechanisms and health benefits. *Nutrients*.
- [3]Roehrs, M., et al. (2017). Citrus flavanones and cardiovascular disease. *Critical Reviews in Food Science and Nutrition*.