Flavones

Bio-Activity Analysis
Bioavailability: Natural vs Synthetic
SCIENTIFIC DATA VISUALIZATION
Health Benefits & Sources
Why You Need It
- Brain Health: Flavones cross the blood-brain barrier, potentially protecting neurons from damage and improving memory.
- Anti-Inflammatory: They inhibit enzymes that trigger inflammation, offering natural relief similar to over-the-counter NSAIDs.
- Blood Sugar Control: Research suggests they improve insulin sensitivity, helping your body manage glucose levels more effectively.
- Antioxidant Power: They neutralize free radicals, preventing cellular damage that leads to aging and disease.
Deep Dive
Flavones, including compounds like apigenin and luteolin, function as powerful biological modulators. One of their most exciting roles is their ability to inhibit an enzyme called COX-2, which is a major driver of inflammation. By keeping this enzyme in check, flavones help soothe the body naturally. Furthermore, they interact with signaling pathways in the brain, specifically those involved in learning and memory formation. This makes them a key focus in research regarding neurodegenerative conditions. Because they are chemically similar to estrogen, they can also bind to estrogen receptors, potentially offering a balancing effect on hormones depending on individual health status.
Natural Food Sources
Flavones are concentrated in the skins and leaves of plants. The 'bitter' compounds in herbs are often flavones in action.
| Food | Amount | % DV |
|---|---|---|
| Celery (Seeds/Stalks) | Moderate | N/A |
| Chamomile Tea | High | N/A |
| Red Peppers | Moderate | N/A |
| Parsley | High | N/A |
| Olives (Green/Black) | Moderate | N/A |
Supplementation
Flavones are rarely found as a standalone supplement. Instead, they are usually taken as a Citrus Bioflavonoid complex or Quercetin supplement (which is chemically related).
Dosage: There is no official Recommended Dietary Allowance (RDA). However, supplement doses typically range from 250mg to 500mg daily.
Who should take it? Individuals looking to reduce systemic inflammation, support seasonal allergy relief, or enhance cognitive function may benefit.
Top Food Sources
Frequently Asked Questions
Safety & Side Effects
Safety & Interactions
Generally Safe: Consuming flavones through food is considered extremely safe for everyone.
Supplement Caution:
- Pregnancy/Breastfeeding: Avoid concentrated supplements; stick to food sources.
- Blood Thinners: Flavones can have mild blood-thinning effects. If you take Warfarin or similar drugs, consult your doctor.
- Hormone Sensitive Conditions: Because they act like weak estrogens, people with hormone-sensitive cancers should avoid high-dose supplements.
- Side Effects: High doses may cause nausea or headaches in sensitive individuals.
Scientific References
- [1]Ultra, C., et al. (2020). 'Flavones and their role in brain health.' *Neural Regeneration Research*.
- [2]Hollman, P. C. (2004). 'Absorption and health effects of flavones.' *Proceedings of the Nutrition Society*.
- [3]Patel, R. V., et al. (2018). 'The role of flavones in diabetes management.' *Journal of Diabetes & Metabolic Disorders*.